i-Series Features




Automation and Remote Operation/Monitoring that Encourage a New Working Style

With FlowPilot, mobile phase monitoring, and other functions, that engineered by Analytical Intelligence, and LabSolutions™ Direct can provide an automated workflow together with remote operation and monitoring from instrument startup to analysis completion.
Automated workflows incorporate the operational expertise of experienced analysts in order to collect data over extended period of time, reduce activities that must be performed in the laboratory, and improve work efficiency.


Using Networks for More Improvements in Work Efficiency

LabSolutions CS allows remote operation and monitoring of all instruments on the analytical network from any locations, even from home.∗ Analysis data and reports are managed on a centralized database where administrative authorization allows managers to assign appropriate operational restrictions to operators, depending on their expertise and rank.

∗ Must have a network in place that is appropriate for the workflow.


Mobile Phase Monitoring

Preventing Mobile Phase Depletion for Continuous Analysis 

Mobile phase monitoring function∗1,∗2 automatically monitors mobile phase volumes so multiple analyses can be performed continuously without fail. If the monitoring function detects, either before start of analysis or during analysis, that a mobile phase is likely to become depleted, a notification is sent to the operator’s computer or smart device to recommend replenishment. This removes the need for repeated instrument checks and mobile phase replenishment and thus prevent re-analysis, therefore prevents any system downtime.

1 Optional
2 Monitors up to 12 liquids when using 1-liter bottles, and up to 4 liquids when using large-volume bottles (2- to 5-liter bottles).


Mobile Phase Flowrate Control Function

Automating Manual Operations for Experienced Users 

The i-Series auto-startup and mobile phase flowrate control function (FlowPilot) can start instruments automatically without burdening the instrument or consumables. This prevents system breakdown and reduces operational cost, while providing highly reliable data over extended period of time.


Remote Operation/Monitoring Function

Operate and Control Instruments from Outside the Laboratory

Using LabSolutions Direct, instruments can be operated remotely to implement pre-configured methods and batch analyses from remote locations outside the laboratory from the web browser of a computer or a smart device.
Instrument status and chromatogram can also be monitored remotely to reduce the time and labor required to travel to and from the laboratory and improve the work efficiency of analysts.



Applications for Analytical Intelligence are not limited to automating the analytical workflow or remote operations. By aggregating and automating the knowledge and skills of experienced analysts, Analytical Intelligence enables anyone to obtain reliable data and analytical results.
Analytical Intelligence is also designed for high levels of compatibility with other instruments and comes with a method migration function, thereby creating a work environment where anyone is equally capable to obtain data without the need for complex procedures to resolve the compatibility between different systems.


i-PeakFinder Automatic Peak Integration Function

Process Large Volumes of Data with High Precision in a Single Step

Processing baseline undulation and noise-obscured peak is a labor-intensive process that can lead to different results based on the experience level of the analyst. Shimadzu’s proprietary i-PeakFinder peak integration algorithm is perfect for troublesome chromatograms like this. 
The i-PeakFinder algorithm is designed to process large volumes of data with high precision in a single step, thereby enabling the user to interpret data acquired more rapidly through simultaneous analysis of multicomponent analytes.


ACTO Method Migration Support Function

Supporting Instrument Replacement and Method Migration 

Migrating a test method (analytical conditions or method) from one instrument to another while obtaining the same chromatogram can be a challenging process. The i-Series is designed with the same internal system volumes as previous Shimadzu systems and competitor systems to ensure system compatibility, and data reproducibility. An Analytical Condition Transfer and Optimization (ACTO) function also adjusts gradient start time automatically, hence analyst can make adjustments to separations obtained by gradient analysis easily.


i-PDeA II Peak Deconvolution Function

Preventing Components being Missed Due to Inadequate Separation

The i-PDeA II peak deconvolution function uses a multivariate curve resolution alternating least squares (MCR-ALS) method to enable qualitative and quantitative analysis of peaks not fully separated by the column. The i-PDeA II can also be used to check the purity of target peaks. (Only available when using a PDA detector and LabSolutions.)




User Interface

Simplifying i-Series Operation

The user interface replicates system flow channel and is used to visually check the operating status of the system. Method editing can also be performed from the same screen. With its intuitive design, even users who are completely new to liquid chromatography can navigate the user interface with minimal training.



Maintenance Videos

Supporting the Replacement of Consumables

Reading a QR Code® shown on the touch panel directs the user to a website with instructional videos on maintenance. This feature helps improve system availability and increases efficiency.


Auto-Validation Function

Stable Operation from System Startup

An auto-validation function means anyone can follow a set procedures and verify the instrument condition easily. The auto-validation function examines solvent delivery stability, wavelength accuracy, absorbance accuracy, gradient accuracy, the presence of any drift/noise, and other parameters. Also, an instrument check function automatically carries out the routine inspections performed before instrument operation and creates a report showing system self-diagnostic results along with a record of consumables usage, including total solvent volume delivered by the delivery pump, total number of injections performed by the autosampler, and the number of hours the lamp has been illuminated. The system check function also manages auto-validation results, making it easy to accurately determine the operating status of the instrument.

Starting Auto-validation

Procedures, mobile phases, and other information necessary for validation are displayed on the screen, allowing you to perform inspections by simply following the instructions.


Creating a System Check Report

Validation results can be viewed from the i-Series main unit. Validation results can also be output in a report format from a workstation.



Maximum Reliability and Stability

− Fundamental functions assure analysis results −


Open Access Sample Placement

A direct access mechanism on sample racks allows the user to place the sample on racks that are not involved in sample injection even during analysis. Furthermore, racks can be shared by multiple analysts, without interrupting the analysis of samples placed by others. Overall, this function enhances work efficiency.


System Monitoring via Smart Devices

System status and chromatograms can be viewed remotely from smart devices and home computers. Situations can be checked without needing to visit the laboratory.


Dual-Temperature Control with TC-Optics and Flow Cells

Excellent Baseline Stability

In addition to the temperature control function for flow cells, the i-Series employs new temperature control technology for detector optical systems, known as TC-Optics (Temperature Controlled Optics). This ensures a more stable baseline that is less susceptible to room temperature variation and increased precision during verification testing and quantitative testing of trace components.


Ultra-Low Carryover Performance Enables High-Sensitivity Analysis

Improved Reliability of Trace Component Analysis

Shimadzu’s proprietary flow channel design, parts, and materials reduce the carryover effects of sample residue to almost zero. Ultra-low carryover performance has been improved to 0.0025% (chlorhexidine, assigned conditions), thereby providing highly precise quantitative performance when analyzing complex samples.



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