Method Package for Veterinary Drug Method Package

Introducing the Veterinary Drug Method Package

 

On May 29, 2006, a positive list system that prohibits the sales of foods with any residual pesticides, feed additives and veterinary drugs in excess of fixed amounts was created. As a result, criteria for residues in foods and analytical methods were determined for about 800 pesticides and veterinary drugs. This number is expected to increase further in the future. LC/MS/MS is often used for these analyses. This method package is pre-registered with analysis conditions and compound information of target components for 42 veterinary drugs for which residual standards and LC/MS analytical methods have been set in the positive list system. Analysis can now be started without performing difficult or time-consuming tasks required in LC/MS/MS analysis, such as evaluating the separation conditions and optimizing the MS parameters for each compound, to allow efficient batch analysis of multiple components.  

 

Analysis Example

The following shows an MRM chromatogram obtained using the batch analysis method file for veterinary drugs.

 

 

Compounds Registered to the Method Package
 

 

Analytical Conditions
 

Analytical column:           

Shim-pack HR-ODS (150 mmL. X 3.0 mmI.D., 3.0μm)
Mobile phase A: 0.1% formic acid – Water
Mobile phase B: Acetonitrile
Flow rate: 0.4 mL/min (gradient elution)
Injection volumne: 10μL
Oven temparature: 40

 

Specifications
 

Applicable model: LCMS-8030, LCMS-8040, LCMS-8050

Workstation: LabSolutions LCMS Ver.5.41 or later

Product components: Method files, report format files, method parameter list (text file containing measurement parameters for each component)

 

Remarks and Precautions

  1. Shimadzu makes no warranty regarding the accuracy of information included in the database or the usefulness of information obtained from using the database.
  2. Be sure to perform tests using standard samples to confirm qualitative and quantitative information obtained with the given system.
  3. To reliably identify registered substances using this database, measure samples using the instrument parameters specified in the method template files included in the product.