Based on its stable labeled internal standards' expertise, Alsachim, a Shimadzu Group company, ​offers ready-to-use LC-MS/MS reagent kits developped in-house to support your daily work.

Turnkey solution for TDM

DOSIMMUNE reagent kit - Alsachim
We propose ready-to-use reagent kits, allowing the simultaneous quantification of different drugs in complex matrix, and composed of:
  • 3 sets composed by: calibrators (with 6 levels + blank), internal standards and quality controls
  • Ready-to-use consumables: Mobile Phase A, Mobile Phase B, Cleaning Solution Phase, analytical column, trap column, reconstitution buffer, LC vials and caps, microtubes

Quantify drugs to optimise the Therapeutic Drug Monitoring

- Quantification of immunosuppressants drugs to optimize the treatment of transplant patients 


DOSIMMUNE™ - Immunosuppressants in whole blood
Parameters: cyclosporin A, Everolimus, Sirolimus and Tacrolimus

More information 

DOSIMYCO™ - Immunosuppressants in human plasma 
Parameters: Mycophenolic acid (MPA) and its glucuronide (MPA-G)

- Detect new and "old" antocoagulants to treat and prevent thromboembolism 

DOSINACO™ - anticoagulants in human plasma
Parameters: Acenocoumarol, Apixaban, Argatroban, Betrixaban, Dabigatran, Edoxaban, Fluindione, Rivaroxaban, Warfarin

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Key benefits of reagent kits

  • Standardized
    routine operation, make interlaboratory comparison easier
  • Time saving
    ready-to-use and optimized method
  • Traceability and Quality
    with Carbon 13 and Deuterium internal standards developed in-house 
Reagent kits are developed and produced by Alsachim, a Shimadzu group company.
Contact your local distributor to get more information about the diagnostic kits
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