UFsensitivityTM

UFsensitivityTM

High Sensitivity for Trace Quantitative Analysis

■ Heated ESI Probe



In order to improve desolvation efficiency, the newly developed heated ESI probe combines a high-temperature gas with the nebulizer spray, assisting in the desolvation of large droplets and facilitating ionization. This development allows for high-sensitivity analysis of a wide range of target compounds.

 

 Excellent Reproducibility Even at Attogram (ag) Levels

 

Both sensitivity and reproducibility are essential when establishing low limits of quantitation. High-precision quantitative results obtained with the LCMS-8050 in the analysis of Verapamil in blood plasma at levels between 500 ag and 50 pg are shown below. Excellent reproducibility with a % RSD of 2.77 % was obtained when analyzing just 500 ag of Verapamil. The LCMS-8050 demonstrates optimal performance for quantitative analysis of even trace components of a complex matrix.


Concentration

actual

ng/mL
Calculated

concentration

ng/mL
% RSD

(n = 6)
Accuracy

(%)

(n = 6)
0.000500 0.000501 2.77 100.2
0.00500 0.00496 3.98 99.2
0.0500 0.0506 1.21 101.2
0.500 0.493 1.31 98.6
5.00 4.89 1.81 97.8
50.0 51.6 0.65 103.2
 

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