MALDI-Based Instruments Comparison
MALDI-Based Instruments Comparison
This page provides a quick overview of 7 models of MALDI-Based Instruments. Choose the model that best suits your analysis needs from the compact digital ion trap MS for on-the-spot analysis, the benchtop MALDI-TOF MS for routine analysis to the research grade MALDI TOF/TOF MS for a diverse range of applications.
 
Contents
1. Summary of Product Features
“Minimum” footprint
With its simple configuration and compact size, it is possible to install the MALDImini-1 in places where mass
analysis devices could not previously be used. 
“Minimum” time
Miniaturization allows rapid, "on-the-spot" analysis and simplifies data acquisition.
“Minimum” sample volume
Complex structural analysis can be performed even with sub-µL sample volumes.
Best-in-class sensitivity and resolution
Easily detect analytes for your application
Quickest to your result
Fast (200 Hz) solid-state laser and fast sample instruction using load-lock chamber
Small footprint/benchtop design
The smallest instrument in its class – saves your valuable laboratory space
Solutions for all your applications
Food & cosmetics, teaching & research labs, regulatory & manufacturing Labs
Highly flexible research-grade MALDI TOF/TOF mass spectrometer
From high energy MS/MS of proteomics and other biological and organic samples to uncompromised analysis of high mass intact proteins
High performance in a robust and flexible design
Uncompromised linear mode performance for high mass analysis
Application-centric solutions
Provides total support for protein identification, LC-MALDI and biomarker discovery
Specifications
| Benchtop Instruments | Floor Standing Instruments | |||||
|---|---|---|---|---|---|---|
| Measurement type  | 
			
			 Digital Ion Trap 
			 | 
			Linear-TOF | Linear-TOF | Linear-TOF | Linear/Reflectron-TOF Reflectron-TOF/TOF  | 
			Linear/Reflectron-TOF Reflectron-TOF/TOF  | 
		
| Measured ion  | 
			
			 Positive 
			 | 
			Positive | 
			 Positive and Negative 
			 | 
			Positive and Negative | Positive and Negative | Positive and Negative | 
| Mass range (m/z) | 650-70,000 | 
			 1-500,000 
			(Linear mode)  | 
			
			 1-500,000 
			(Linear mode)  | 
			1-500,000 (Linear mode)  | 
			1-500,000 (Linear mode) 1-80,000 (Reflectron mode)  | 
			1-500,000 (Linear mode) 1-80,000 (Reflectron mode)  | 
		
| MS/MS function | CID up to MS3  | 
			
			  - 
			 | 
			
			  - 
			 | 
			- | Post Source Decay (PSD)  | 
			CID | 
| Mass Resolution | > 4,000 | 
			 > 5,000 
			 | 
			
			 > 5,000 
			 | 
			> 5,000 | > 5,000 (Linear mode) > 15,000 (Reflectron mode)  | 
			> 5,000 (Linear mode) > 20,000 (Reflectron mode)  | 
		
| Mass accuracy | External : 200 ppm | 
			 Internal : 20 ppm 
			External : 150 ppm  | 
			
			 Internal : 20 ppm 
			External : 150 ppm  | 
			Internal : <30 ppm External: <200 ppm  | 
			Internal : 10 ppm (Refrectron mode) 30 ppm (Linear mode)  | 
			Internal : 5 ppm (Refrectron mode) 30 ppm (Linear mode)  | 
		
| Throughput | 0.3, 0.6 spectrum/s (Depend on mass range and scan speed) | 
			 50, 100, 200Hz (Variable) 
			 | 
			
			 50, 100, 200Hz (Variable) 
			 | 
			1 - 50 Hz (Variable) | 1 - 50 Hz (Variable) | 
			 1 - 50 Hz (Variable) 
			 | 
		
| Dimensions/ Weight | W309 × D385 × H320 mm 25 kg  | 
			
			 W600 × D745 
			× H1,055 mm 86 kg  | 
			
			 W600 × D745 
			× H1,055 mm 92 kg  | 
			W700 × D850 × H1,920 mm 330 kg  | 
			W700 × D850 × H1,920 mm 345 kg  | 
			
			 W700 × D850 
			× H1,920 mm 375 kg  | 
		
| Type | Benchtop | 
			 Benchtop 
			 | 
			
			 Benchtop 
			 | 
			Floor standing | 
			 Floor standing 
			 | 
			
			 Floor standing 
			 | 
		
Applications
| Benchtop Instruments | Floor Standing Instruments | |||||
|---|---|---|---|---|---|---|
| Peptide mass fingerprinting | 
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| Protein sequencing | 
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| Glycans/ Glycopeptides investicgation  | 
			
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| Synthetic peptides and Proteins | ![]()  | 
			
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| Screening analysis | 
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| Cell culture | ![]()  | 
			
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| Food/ Cosmetics  | 
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| Small molecules | 
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| QA/QC | 
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| Polymer analysis | 
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| Oligonucleotide/ Primer analysis | ![]()  | 
			
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| Biomarker discovery  | 
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| Proteomics | ![]()  | 
			
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| High-energy MS/MS of proteomics and other biological /Organic samples | 
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| High-mass intact proteins | ![]()  | 
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| MS Imaging | ![]()  | 
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3. Principle of MADI-TOFMS

What is MALDI?
MALDI is the abbreviation for "Matrix Assisted Laser Desorption/Ionization."
The sample for MALDI is uniformly mixed in a large quantity of matrix…



