AAIC 2021
26.07.2021 - 30.07.2021
VIRTUAL Conference
AAIC 2021 | Alzheimer's Association
"Discover our innovative platforms and proven solutions for advanced healthcare"
Join us on our virtual booth!
Shimadzu is a leading driver in developing healthcare solutions with technology developments ranging from advanced imaging systems for use in medical diagnosis and treatment, engineering mass spectrometry-based solutions for exploring ways to discover disease biomarkers as well as building MS solutions for daily routine quantitation in biological fluids. Discover all our solutions at the virtual booth!
Posters
Poster #51562 - Semi-quantitative assay for Neurogranin peptides using IP-MALDI-MS
Authors: Naoki Kaneko, Ryota Takahashi, Akihito Korenaga, Ritsuko Yoda, Sadanori Sekiya, Shinichi Iwamoto, Koichi Tanaka
Koichi Tanaka Mass Spectrometry Research Laboratory, Shimadzu Corporation, Kyoto, Japan
Poster #51969: Analytical Validation of Plasma Amyloid β Measuring System by Immunoprecipitation-Mass Spectrometry
Authors: Ritsuko Yoda1, Naoki Kaneko1, Akihito Korenaga1, Shinji Funatsu1, Nanami Sakashita1, Takashi Nishikaze1, Yuko Ohashi2, Mamoru Honda2, Yusaku Hioki1, Sadanori Sekiya1, Koretsugu Ogata1, Shinichi Iwamoto1, Kazushige Tsujino2, and Koichi Tanaka1
(1)Shimadzu Corporation, Kyoto, Japan, (2)Shimadzu Techno-Research, Inc., Kyoto, Japan
Poster #51555: The APP669-711/Aβ1-40 ratio as a plasma biomarker specific for the brain Aβ deposition in APP/PS1 mouse
Authors: Naoki Kaneko1, Masaya Matsuzaki2, Miyabishara Yokoyama2, Akihito Korenaga1, Sadanori Sekiya1, Shinichi Iwamoto1, Koichi Tanaka1, Taisuke Tomita2
1 Koichi Tanaka Mass Spectrometry Research Laboratory, Shimadzu Corporation, Kyoto, Japan
2 Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan
Scientific publications
Does the Plasma Amyloid-β Composite Biomarker Associate with Cognitive Decline in Preclinical Alzheimer's Disease? IP-MS will answer. here
IP-MS Technology introduction here
Collaborative Research Partner: Prof. Colin L Masters, The Florey Institute, The University of Melbourne here

Shimadzu Advanced Healthcare
Find more here
MALDI Lineup

MALDI-8020
Linear mode instruments have traditionally been the instruments of choice in MALDI‒TOF‒based quality control (QC) and profiling workflows, and the MALDI‒ 8020 is no exception. Peptides, proteins, polymers or oligonucleotides ‒ the instrument is capable of delivering the performance required for QC applications. Research laboratories will also benefit from the MS capabilities of the instrument through the rapid mass‒measurement of samples.

MALDImini-1
By combining a MALDI ion source with Digital Ion Trap (DIT) technology, it is possible to carry out high-sensitivity MS and MSn analysis even on micro-quantity samples. Not only can the mass of various molecules be checked, but it is also possible to carry out a wide range of analyses such as identifying proteins and investigating the structure of glycans and glycopeptides.

AXIMA Assurance
An affordable, robust Linear MALDI-TOF mass spectrometry for all laboratories requiring routine manual or automated analysis of a wide variety of sample classes.Used to detect presence and ratio of amyloid beta in blood samples after immunoprecipitation.
LCMS-TQ Lineup

LCMS-8060NX
The LCMS-8060NX is a triple quadrupole mass spectrometer with high-class sensitivity and detection speeds together with proven robustness.A perfect tool for clinical research and quantitation of phosphor-TAU in biological fluids.
LCMS-High Resolution Lineup

LCMS-9030
The quadrupole time-of-flight (Q-TOF) LCMS-9030 system is a research grade mass spectrometer designed to deliver high-resolution, accurate-mass detection with incredibly fast data acquisition rates, allowing scientists to identify and quantify more compounds with greater confidence.
Imaging instrument Lineup

LABNIRS & LIGHTNIRS - Toward Next-Generation Optical Brain-Function Imaging
Just how the human brain functions remain one of the greatest unsolved puzzles. To solve this mystery, brain-function imaging for visualization of brain functions has developed rapidly in recent years. In particular, in vivo optical imaging by functional near-infrared spectroscopy (fNIRS) has attracted attention as a technique that supports next-generation brain science.Utilizing its leading-edge science and technology, Shimadzu has developed the LABNIRS/LIGHTNIRS, thereby contributing to the still growing field of brain science