With different pore sizes, Shim-pack Bio Diol LC columns are effective for analysis of aggregates and fragments of mAb, oligonucleotides and carbohydrates.
Nexera XS inert - Columns
Ultra High Performance Liquid Chromatograph
Selecting Analytical Columns Based on Target Components and Objectives
Shim-pack™ Series Columns
Analyzing biomolecules, such as proteins and nucleic acids, requires using columns intended for a variety of separation modes. In particular, samples sensitive to metal ions require a column that is optimized to reduce adsorption. Shimadzu offers columns optimized for a wide variety of molecules.
Mode | Ion exchange | Size exclusion | Hydrophobic Interaction | Reversed phase | |
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Product | Shim-pack Bio IEX | Shim-pack Bio Diol | Shim-pack Bio HIC | Shim-pack Scepter | Shim-pack GISS |
Application | Peptide mapping |
LC Columns
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Shim-pack Bio IEX Columns are available in Q (quaternary ammonium) and SP (sulfopropyl) chemistries and are based...
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Shim-pack Bio HIC Column is a hydrophobic interaction chromatography (HIC) column packed with butyl bonded hydrophilic...
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Even for LC columns that claim to be designed for basic compounds, adequate resolution often can not be obtained due to problems such as leading of highly polar basic compounds, peak shape deterioration of acidic compounds, or long equilibration time required for low ionic strength acidic mobile phase.
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Excellent stability and performance could be achieved under a wide range of LC conditions with Shim-pack Scepter LC columns, which are the next generation organic silica hybrid based columns.
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Designed to maximize performance of LC systems, Shimadzu's Shim-pack Velox columns with core shell technology enable you to achieve increased separations and faster analysis times on any LC platform.